• The most common pathology associated with FGR is poor

  2019-11-25

  

  The most common pathology associated with FGR is poor placental perfusion as a result of abnormal placentation [4]. Placental developmental disorders and insufficient hormone synthesis may lead to FGR [5,6]. However, the exact mechanism responsible for abnormal placental development remains unclear.

• 2-Deoxycytidine Cantharidin is a natural element extracted f

  2019-11-25

  

  Cantharidin is a natural element extracted from blister beetles, and has been proven to be effective in cancer [16]. NCTD, the demethylated analog of cantharidin, has been synthesized and been shown to have an equal anti-cancer effect with fewer side effects than cantharidin [39]. It was confirmed t

• Interestingly selective ETA blockade increased cutaneous blo

  2019-11-22

  

  Interestingly, selective ETA blockade increased cutaneous blood flow as measured by laser Doppler fluxmetry. This is a measure of total blood flow in the different vessels in the skin including venules, IL-10, human recombinant protein synthesis as well as arterioles. This finding is in accordance

• Among the different factors that modulate Schwann

  2019-11-22

  

  Among the different factors that modulate Schwann cell biology, several studies pointed out the role played by neuroactive steroids, in particular progesterone (P4) and its derivatives dihydroprogesterone (DHP) and allopregnanolone (ALLO). Schwann Biapenem are steroidogenic, possessing the entire en

• Our results are the first to demonstrate that

  2019-11-22

  

  Our results are the first to demonstrate that ERRγ acts as a catabolic regulator of cartilage degeneration and OA pathogenesis, and collectively support the idea that ERRγ could be a therapeutic target for OA Introduction DNA cytosine-5-methyltransferases (Dnmts) catalyze the methyl transfer fr

• In the present study real

  2019-11-22

  

  In the present study, real-time polymerase chain reaction also confirmed that gene expressions of RT1 class II, locus Bb (RT1-Bb) was up-regulated and Spi-B transcription factor (Spib) was downregulated at day 3 after the VMH lesions. These two genes work as one of immune responses. RT1-Bb controls

• Introduction Protein ubiquitination is a

  2019-11-22

  

  Introduction Protein ubiquitination is a posttranslational modification that plays a major role in almost all cellular processes in eukaryotes (Hochstrasser, 2009; Komander & Rape, 2012). It involves the covalent attachment of ubiquitin (Ub) via its C-terminal glycine carboxylate to a primary amine

• Family and twin studies have estimated the heritability of

  2019-11-22

  

  Family and twin studies have estimated the heritability of obesity to be between 40 and 70% [5], [6], [7]. However, all known risk variants can only account for ∼3% of the variance in BMI [8], [9]. Therefore, alternate methods are needed to identify additional risk factors. In recent decades, Drosop

• Functional studies suggested the presence of a cysLT

  2019-11-22

  

  Functional studies suggested the presence of a cysLT1 receptor. We observed an LTD4-induced cytosolic calcium response, albeit one that was very weak by most standards. The magnitude of the average response was partially explained by the low percentage of Beauvericin showing a very transient respon

• apelin Methylated CpGs can recruit transcriptional

  2019-11-22

  

  Methylated CpGs can recruit transcriptional co-repressors to prevent transcription factors (TFs) from promoting gene expression by tightly packing apelin structures [38]. Two CpG islands in the IPT5b promoter region showed higher methylation level in M9 rootstock compared to Mr (Fig. 3b). However,

• br Conclusions Enzyme can be delivered to the tumour by

  2019-11-22

  

  Conclusions Enzyme can be delivered to the tumour by using humanised or fully human GSK2656157 mg or even loaded into synthetic nanospheres produced from silica [64] or liposomally entrapped [65]. For any future ADEPT developments, a number of basic points need to be considered. As immunogenicity

• Introduction Klebsiella pneumoniae a Gram

  2019-11-22

  

  Introduction Klebsiella pneumoniae, a Gram-negative enteric bacterium, is an organism with significance in both biomedicine and biotechnology. Some of the strains of K. pneumoniae are opportunistic pathogens, which can cause suppurative infection, pneumoniae and urinary tract infection in humans (B

• Another significant finding in our study was the demonstrati

  2019-11-22

  

  Another significant finding in our study was the demonstration that the axon-protective action associated with CK2 inhibition correlated with preservation of mitochondrial structure and function in DRB (Fig. 11). Because of the consistent protection conferred by CK2 inhibition during OGD, improved a

• During recent years two primary types of models have

  2019-11-21

  

  During recent years, two primary types of models have been applied for calculating various thermodynamic properties of amino 1,4-DPCA solutions, i.e. excess Gibbs energy (gE) models used numerously to describe the solubility of amino acid solutions, and equations of state (EOS) models appropriate to

• Among the members of the GH family which groups

  2019-11-21

  

  Among the members of the GH106 family, which groups 319 different sequences, a single 3D-structure has been reported, the BT0986 from Bacteroides thetaiotaomicron that shows a (β/α)8 barrel and catalyzes the hydrolysis of an α-l-rhamnopyranoside bound to the C2 position of an arabinofuranoside (L-Rh

16024 records 950/1069 page Previous Next First page 上5页 946947948949950 下5页 Last page