• The CYP A genes are regulated physiologically by glucocortic

  2021-05-05

  

  The CYP3A genes are regulated physiologically by glucocorticosteroids, growth hormone, thyroid hormones and cytokines [13, 20, 30]. It has been shown that glucocorticoid receptor (GR), pregnane X receptor (PXR), constitutive androstane receptor (CAR) and vitamin D receptor (VDR) play an important ro

• br Introduction Accounting educators and professional accoun

  2021-05-05

  

  Introduction Accounting educators and professional accounting organizations have speculated that advanced placement (AP) may be an effective tool for recruiting high-quality students into accounting education programs (Deines, Bittner, & Eichman, 2012; The Pathways Commission, 2012), and it is no

• WZ3146 Pahlavanzadeh and Fakouri Baygi employed PC

  2021-05-05

  

  Pahlavanzadeh and Fakouri-Baygi [6] employed PC-SAFT EoS to predict the WZ3146 of carbon dioxide by aqueous MEA solutions. They used the ideal form of Smith–Missen algorithm to calculate liquid phase concentrations. The results illustrate acceptable accuracies so that the AAD was achieved equal to 3

• br Acknowledgments This work was funded

  2021-04-30

  

  Acknowledgments This work was funded by the EU ERDF and the Spanish Ministry of Economy and Competitiveness (MINECO) under Project TIN2013-41576-R, and the Spanish Ministry of Education, Culture and Sport (MECD) under a FPU grant (AP2010-3259), and the Andalusian Regional Government (Spain) under

• Introduction Hematopoietic stem cells HSCs in

  2021-04-30

  

  Introduction Hematopoietic stem Bikinin (HSCs) in the adult bone marrow (BM) provide all types of blood cells throughout life, while also self-renewing to maintain blood homeostasis. Blood/marrow stem cell transplantation is the most advanced method to cure patients suffering from hematological ma

• br Results and discussion br Conclusions In this

  2021-04-30

  

  Results and discussion Conclusions In this work, we have conjugated two thermophilic enzymes (i.e., AMY and LASPO) to iron oxide NPs through different conjugation strategies obtaining efficient biocatalysts. We have demonstrated that these NP-enzyme systems can be successfully activated by an

• Adding more pieces to the puzzle using a

  2021-04-30

  

  Adding more pieces to the puzzle, using a human-to-animal crossover study, blood taken from healthy volunteers that underwent exercise was used as a dialysate to perfuse a rabbit heart in a Langendorff model of MI [62]. Unprecedentedly, dialysate of plasma from exercised humans reduced infarct size

• The in vitro enantioselective metabolism of

  2021-04-30

  

  The in vitro enantioselective metabolism of pesticides has been investigated by employing human liver microsomes, which are a reliable resource to perform MCL enantioselective risk assessment in humans (Carrão et al., 2019; de Albuquerque et al., 2018, 2016; Yao et al., 2016). The enantioselective m

• br STAR Methods br Microenvironmental niches for na ve

  2021-04-30

  

  STAR★Methods Microenvironmental niches for naïve and activated B cells Secondary lymphoid organs, such as the spleen and lymph nodes, are structurally and functionally compartmentalized to provide a set of microenvironmental niches that support the survival of resting B cells, as well as the a

• Through an unknown mechanism RING Ubox

  2021-04-30

  

  Through an unknown mechanism, RING/Ubox-type E3 dimers and the N-terminal tail have been shown to function as a modulator of full E3 ubiquitin ligase activity [27]. LRSAM1 promotes a significant enhancement in the formation of the high-molecular-weight products or E3 activity when the RING domain is

• Similarly synthetic analogs of Alogliptin by replacing the

  2021-04-30

  

  Similarly synthetic analogs of Alogliptin by replacing the cyanobenzyl group with the butynyl group have been synthesized and tested as selective DPP-4 inhibitors [7], [8]. Additionally, quinazolines [9], [10], pyridopyrimidinediones [11], pyrazolopyrimidinones [12] and pyrimidines [13] as DPP-IV in

• A range of inhibitors were therefore synthesized containing

  2021-04-30

  

  A range of inhibitors were therefore synthesized containing either carboxylic simvastin or ester functionality at the ‘tail’ group as well as variations in the ‘head.’ These were assayed in vitro using the DCIP assay for binding affinity against and human DHODH at 50μM, respectively (). Analysis

• The regression also revealed a

  2021-04-30

  

  The regression also revealed a significant association between admission selectivity (SELECT) and exam pass rate (PASS%) (p Tiplaxtinin serve as an indicator of a student’s ability to learn and their aptitude for academic success. These same qualities likely enable more selective schools to design m

• Future analysis could consider using fixed

  2021-04-30

  

  Future analysis could consider using fixed effects also with the level set field, , in order to investigate which covariates explain the classification, a feature of the proposed model that we have not yet investigated. Further, multi-type point patterns may also be analyzed with the proposed model

• Several large scale clinical studies have set

  2021-04-29

  

  Several large-scale clinical studies have set out with the common goal to further understand the cognitive impact of menopause and hormone therapies taken by women (Gleason et al., 2015, Greendale et al., 2011, Karlamangla et al., 2017, Rapp et al., 2003, Shumaker et al., 2003). Only one human study

15986 records 673/1066 page Previous Next First page 上5页 671672673674675 下5页 Last page