• In bone PGE exerts both anabolic and catabolic

  2021-05-26

  

  In bone, PGE2 exerts both anabolic and catabolic effects [6], [7], [8], [9]. Administration of PGE2 to mice lacking each of the four prostanoid receptors identified EP4 as the primary mediator of PGE2-induced bone formation [10]. While the role of EP1 in osteoblastic differentiation and bone metabol

• Quantum dots QDs which exhibit excellent fluorescence

  2021-05-26

  

  Quantum dots (QDs), which exhibit excellent fluorescence quantum yields (QYs), high extinction coefficients and size-tunable narrow emission have highly attracted great interest in various applications such as in solar cells, sensors, and bioimaging [16], [17], [18], [19], [20]. However, QDs suffere

• On the opposite side sPLA

  2021-05-26

  

  On the opposite side, sPLA2-X has also been implicated in the pathology of cancer [167,168]. Human sPLA2-X induces lipid droplet formation in Ras-driven MDA-MB-231 triple-negative breast cancer NECA and promotes their survival during nutrient stress. It acts through the products of its enzymatic ac

• Ultrasound is an acoustic wave with a frequency kHz that

  2021-05-26

  

  Ultrasound is an acoustic wave with a frequency >20 kHz that needs a medium to propagate [20]. Accompanied by the spread of an ultrasonic wave, a series of alternating cycles of compression and rarefaction emerge in the liquid medium. During the rarefaction cycle, microbubbles are formed because of

• br Cytokine impact on ILC fate Increasing

  2021-05-26

  

  Cytokine impact on ILC fate Increasing evidence shows that ILC2 and ILC3 may convert into ILC1-like AZD2932 by downregulating either GATA3 or RORγt, respectively, upregulating T-bet and gaining the capacity for IFN-γ production [60,61]. This process, often referred to as ‘ILC plasticity’, may be

• The Inhibitor of APoptosis IAP proteins were first identifie

  2021-05-25

  

  The Inhibitor of APoptosis (IAP) proteins were first identified as gene products of baculovirus that inhibited apoptosis of infected insect glibenclamide mg (Clem et al., 1991, Crook et al., 1993). Subsequently, the mammalian IAP family was identified (Rothe et al., 1995, Uren et al., 1996). All mem

• If the unwanted objects detected by OpenComet are manually d

  2021-05-25

  

  If the unwanted objects detected by OpenComet are manually deleted, and then the DNA (%) in tail is computed, the performance of the present method can be compared more effectively. Therefore, performance of OpenComet is analysed in two ways as Approach 1 and Approach 2. Approach 1, considers the DN

• br Introduction Coping with DNA

  2021-05-25

  

  Introduction Coping with DNA damage is possible thanks to surveillance mechanisms (checkpoints), that detect the problem and promote its solution [1], [2], and to repair and tolerance pathways that remove the lesions or reduce the damage consequences [3], [4]. Failures in these processes have a h

• In rats exposed to day

  2021-05-25

  

  In rats exposed to 1 day of nicotine withdrawal (24 h after the last nicotine administration) we expected a decrease of general locomotor activity and a decrease of global striatal dopamine release, which were assessed in a previous study following 14 days of nicotine exposure and 24 h of nicotine w

• Our results indicate that C CoA is formed in

  2021-05-25

  

  Our results indicate that C75-CoA is formed in the hypothalamus following stereotaxic injection of C75. Inhibition of hypothalamic CPT1 by C75-CoA in vivo, as seen in our experiments, is independent of the putative inhibition by malonyl-CoA, which may be formed after the action of C75 either on FAS

• Although the control group and tinnitus

  2021-05-25

  

  Although the control group and tinnitus group do not significantly differ based on age, gender or hearing loss, a limitation of this study is that the control group is only group-matched, and not individually matched. Furthermore, we only tested hearing acuity in tinnitus patients via standard pure

• NPC L expression is both tissue

  2021-05-25

  

  NPC1L1 expression is both tissue- and species-specific. Consistent with its function, NPC1L1 is mainly localized to the brush border membrane of enterocytes and the canalicular membrane of hepatocytes. NPC1L1, which is expressed in the liver of humans and rats but not mice, mediates cholesterol Wort

• Other studies have investigated the role of HDAC inhibitors

  2021-05-25

  

  Other studies have investigated the role of HDAC inhibitors in particular signaling pathways mediated by EWS–FLI1 (Matsumoto et al., 2001). A recent investigation, showed a physical association of EWS–FLI1 and HDAC1 that helps mediate a disruption in the p53 activation of downstream targets (Li et a

• There have been reports regarding the use of

  2021-05-24

  

  There have been reports regarding the use of enolases as novel vaccine candidates for A. suum, S. suis, T. pisiformis and T. multiceps on account of this enzyme class's critical role in plasminogen activation and migration across tissue barriers (Chen et al., 2012; Zhang et al., 2009; Zhang et al.,

• br Asb Proteins and Mitochondrial Function Mitochondria are

  2021-05-24

  

  Asb Proteins and Mitochondrial Function Mitochondria are intracellular organelles in eukaryotic Firefly Luciferase mRNA receptor and are the main sites of oxidative phosphorylation and ATP production. In addition, mitochondria serve as signal transduction docking stations in pyroptosis and regul

16055 records 663/1071 page Previous Next First page 上5页 661662663664665 下5页 Last page