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The S helix of KCNQ consists of a peculiar
2019-04-29

The S4 helix of KCNQ1 consists of a peculiar sequence of positively charged the full details forming a region that is involved in sensing the membrane voltage and controlling the open probability of the channel [27]. In the resting state of the channel, these positively charged side chains are expec
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A proposed diagnostic score system
2019-04-29

A proposed diagnostic score system for BrS, referred to as the Proposed Shanghai BrS Score, is presented in Table 2. These recommendations are based on the available literature and the clinical experience of the Task Force members [8,56–60]. Weighting of variables is based on expert opinion informed
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nitric oxide synthase inhibitors It is possible that this co
2019-04-29

It is possible that this contradiction may be due to referral bias in the studies of Brugada et al. [20,21]. Second, it is possible that time of day influences the results of PES. The magnitude of ST-segment elevation in the right precordial leads in BS varies spontaneously over days and during the
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Payno lleva al lector al centro de la ciudad
2019-04-29

Payno lleva al lector al centro de la ciudad de México para que sea testigo de lo que el hombre es capaz cuando se trata de herir, matar o destruir, con ciudadanos y ejército mexicanos repitiendo en la historia lo hecho por aztecas de antaño, defendiéndose y confirmando en una guerra order Pirfenido
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Por sua vez na Nicar gua
2019-04-29

Por sua vez, na Nicarágua, cmv virus Revolução Sandinista de 1979 foi resultado de um acúmulo de forças sociais heterogêneas –camponeses, operários, pobres e marginalizados da cidade e do campo, intelectuais e setores progressistas da burguesia– em torno de um objetivo comum: liquidar o governo da f
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Scott Mainwaring enfatiza que a ascens
2019-04-29

Scott Mainwaring enfatiza que natural antibiotics ascensão do comunismo e do movimento sindical mobilizou a adesão de boa parte dos católicos ao movimento integralista (de inspiração conservadora). Além das campanhas de “demonização” desta orientação política e de seus membros, a Igreja criou no iní
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Since I created the Doughnut at Oxfam in
2019-04-29

Since I created the Doughnut at Oxfam in 2012, it has been widely applied within academia, policymaking, progressive business, urban planning, and civil society as a tool for reconceptualising sustainable development. Here I present a renewed and strengthened framework, based on recent advances in b
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En cambio la intensidad que cobraron las relaciones con Colo
2019-04-28

En cambio la intensidad que cobraron las relaciones con Colombia y Perú respondió a otra razón. Con este último país Argentina tuvo una tradición de fuertes lazos políticos, culturales y militares. Sin embargo, la relación se modificó cuando Argentina vendió ilegalmente armas a Ecuador durante la gu
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br Methods The Spanish GEM MAS trial
2019-04-28

Methods The Spanish GEM05MAS65 trial lasted from March, 2006 to October, 2008 and included 260 patients from 63 Spanish centers. At study entry, every patient was aged 65 years or older and had newly diagnosed, untreated, symptomatic, measurable MM. These patients had received a homogeneous induc
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All of these factors highlight several key issues when asses
2019-04-28

All of these factors highlight several key issues when assessing sustainable and healthy food systems. First, efficiency indicators, such as litre water use per 1000 kcal or kg greenhouse gas emissions per kg protein draw an incomplete picture, and recommendations based on them will not necessarily
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The osteoid and woven bone can
2019-04-28

The osteoid and woven bone can be seen as interconnected trabeculae (thin or broad) or sheets. The bone surrounding the lesion (host bone) is strong and is made of varying mixtures of woven and lamellar bone [36]. The radiologic appearance of cortical osteoid osteoma arising in the shaft of a long b
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The following is the Supplementary material related to
2019-04-28

The following is the Supplementary material related to this article Video 1, Video 2, Video 3. Discussion In the electrophysiology setting, increased pericardial effusion or tamponade risk is associated with left-sided arrhythmia ablations, biventricular pacemaker placements, and implantable car
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The comparative consensus modelling approach used by Eaton
2019-04-28

The comparative consensus modelling approach used by Eaton and colleagues is now used frequently to justify the implementation of particular HIV interventions. However, this approach produces meaningful results only if the comparison is based on valid models. Most comparative consensus studies (incl
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glucose transporter Asimismo y con distinto nfasis entre s
2019-04-28

Asimismo y con distinto énfasis entre sí, estas crónicas presentan la dimensión de la escritura de la historia como reparación, como sutura del trauma, y también como espacio textual único para la supervivencia de memorias en constante proceso de desaparición. Esto les confiere cierto ubicuo tono de
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br Methods The Spanish GEM MAS trial lasted from March
2019-04-28

Methods The Spanish GEM05MAS65 trial lasted from March, 2006 to October, 2008 and included 260 patients from 63 Spanish centers. At study entry, every patient was aged 65 years or older and had newly diagnosed, untreated, symptomatic, measurable MM. These patients had received a homogeneous induc
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