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ion channels br Alternans and arrhythmogenesis in different
2019-04-26
Alternans and arrhythmogenesis in different clinical conditions APD alternans, whether spatially concordant or discordant, can produce arrhythmias. For example, spatially concordant alternans themselves can produce 2:1 conduction block, thereby initiating re-entry [48]. Nevertheless, discordant a
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br Materials and methods br Results The
2019-04-26
Materials and methods Results The two groups were similar regarding age, sex, systolic blood pressure, diastolic blood pressure, and heart rate (bpm) (Table 1). LV end-diastolic dimension, LV end-systolic dimension, posterior wall thickness, and LV ejection fraction (%) were not statistically
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Nademanee et al reported nine symptomatic
2019-04-26
Nademanee et al. reported nine symptomatic patients with BrS who experienced VF and underwent electrophysiological study and catheter ablation [8]. The patients exhibited abnormal epicardial electrograms characterized by fragmented electrograms with a relatively low voltage ( Idiopathic ventricular
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cerk The OptiVol Fluid Index OVFI which is derived
2019-04-26
The OptiVol Fluid Index (OVFI), which is derived from changes in intrathoracic impedance, can effectively assess HF by analyzing the changes in the intrathoracic impedance detected by the original OptiVol algorithm. Small et al. previously determined that a frequent and extended threshold crossing c
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Patients with syncope often suffer secondary trauma Major mo
2019-04-26
Patients with syncope often suffer secondary trauma. Major morbidities such as fractures and injuries from motor vehicle accidents have been reported in 6% of patients, whereas minor injuries such as lacerations and bruises have been reported in 29% [1]. Recurrent syncope was associated with fractur
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Cisplatin based chemotherapy is commonly used in
2019-04-26
Cisplatin-based chemotherapy is commonly used in adjuvant CCRT, but data on carboplatin-based chemotherapy with radiotherapy is lacking. Khoury et al reported that patients treated with carboplatin-based chemoradiotherapy show worse outcomes. However, the impact on patient comorbidities was not repo
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br Materials and methods br
2019-04-26
Materials and methods Results Discussion To our best knowledge, a multi-modality approach to systematically characterize an OS in vivo orthotopic model, using an aggressive OS cell line has not been previously reported. The advantage of using multi-modality approach i.e. BLI, histopathology
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Given the recognized effects of bisphosphonates in metastati
2019-04-26
Given the recognized effects of bisphosphonates in metastatic breast cancer [14,15] and that potential anticancer effects have been demonstrated in preclinical [16], translational [17], patients with cancer therapy-induced bone loss [18] and GDC-0994 based-studies [19,20] a number of clinical trials
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The cardiac GP are a collection of
2019-04-26
The cardiac GP are a collection of autonomic nervous systems comprising both afferent and efferent as well as sympathetic and parasympathetic fibers [10,11]. Radiofrequency catheter ablation eliminates the most elementary level of vagal innervation by destroying the visceral efferent limb of the par
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Introduction Acute acalculous cholecystitis ACC is defined a
2019-04-25
Introduction Acute acalculous cholecystitis (ACC) is defined as an acute necroinflammatory disease of the gallbladder in the absence of cholelithiasis and has a multifactorial pathogenesis [1]. ACC has very rarely been described in patients undergoing myelosuppressive chemotherapy for acute myelobl
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Even so the purpose of our
2019-04-25
Even so, the purpose of our Comment was to counter the notion that is useful to think in terms of “Ebola suspects” and their ostensible options, while reminding us to question whether the fetishisation of isolation over treatment was “an institutionalized form of non-assistance” that resulted in “a
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The Registrar of Pesticides noted this
2019-04-25
The Registrar of Pesticides noted this effect of order AZD4547 and started banning the most toxic HHPs, initially parathion and methylparathion, in 1984. The exponential rise in total (not just pesticide) suicides then stopped (); the rate began to fall rapidly after 1995, when five further HHPs we
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br Procedural endpoints The most commonly employed electroph
2019-04-25
Procedural endpoints The most commonly employed electrophysiological endpoint is the achievement of noninducibility. While noninducibility has been shown to be predictive for clinical freedom from recurrent VT, it has not been uniformly the case [1,2]. Inducibility of VT is probabilistic and rare
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br Conflict of interest br Introduction Garrigue et al
2019-04-25
Conflict of interest Introduction Garrigue et al. reported that atrial overdrive pacing reduces the number of sleep S63845 episodes in pacemaker patients without heart failure [1]. However, this finding has not been replicated in subsequent investigations [2–5], although some meta-analysis stu
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Obesity with excessive fat was an important
2019-04-25
Obesity with excessive fat was an important risk factor for the occurrence or progression of cardiac arrhythmia. As compared to abdominal fat, the amount of epicardial fat more correlates with the occurrences of atrial fibrillation, which suggests the distinctive arrhythmogenic effects of epicardial
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